Unveiling Genomic Insights: TraDIS Study


We are excited and proud to share a recent achievement at the Ramaciotti Centre for Genomics, showcasing an example of the impactful outputs from our high-quality data and the diverse expertise of our staff, with strong ties to the science community.

In a study recently published by Fabian et al. (2024), our team performed the transposon-directed insertion site sequencing (TraDIS). The Ramaciotti Centre is the only high-throughput service provider offering TraDIS worldwide! One of our staff members, Christie, is a co-author of this study, having contributed to this project as part of her previous role at Macquarie University.

Fabian et al. utilised a TraDIS-based approach to conduct genome-wide analysis of the fitness of thousands of gene mutations in the bacterium Pseudomonas protegens Pf-5 under culture conditions promoting "swimming" motility. The team identified a suite of genes important for swimming, which is a key trait for this microbe's effectiveness as a biocontrol agent against agricultural crop plant diseases.

We invite you to delve into the details of this groundbreaking study and explore the genomic insights it unveils.

Read the full publication here to learn more about this exciting research endeavor.